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The resurrection of the dire wolf after 12,000 years of extinction represents not just a scientific breakthrough but also a novel challenge in animal welfare: how does one properly care for a species that hasn’t existed in the modern era? Colossal Biosciences has developed comprehensive care protocols that prioritize the physical and psychological well-being of these unique animals, setting potential standards for future de-extinction projects.

The three dire wolf pups—males Romulus and Remus (born October 2024) and female Khaleesi (born January More >